Neuron-Gale
Testing galectin-3 inhibitors to reduce neuroinflammation in Alzheimer's mouse models, with a stated focus on peripheral (non-CNS-penetrant) indications.
Documentation note
Included on CerebrumDAO's /projects page (with its own description and a dedicated blog post) but not listed separately in the dashboard's investment summary table — confirmed by CerebrumDAO as part of the public portfolio. Separately, a CDP-19 governance proposal for a similarly-named "Galectin-3 Inhibitors in CNS" study is on record with its own closed vote; whether CDP-19 and this $50,000 line item are the same funding event described two ways, or two distinct ones, is not resolved from public sources alone.
The science
Problem
Neuroinflammation mediated by galectin-3 in Alzheimer's disease.
Approach
Small-molecule galectin-3 inhibition, tested in an Alzheimer's mouse model.
Why CerebrumDAO supported it
Not publicly documented
Researchers & founders
- Dr. Maryna Polyakova (Project Lead, per CerebrumDAO's /projects page — also credited as Science Lead on the SK Channels project)