Project Transfidelity
Therapeutics / Protein SynthesisOngoing, early-stage preclinical discovery; patent not yet filed (per CerebrumDAO's project page)
Improves the accuracy of protein synthesis (translation fidelity) to prevent the misfolding and aggregation implicated in neurodegenerative disease, particularly Alzheimer's.
Documentation note
An identical €75,000 / October 28, 2024 funding figure appears on both this project's page and Arctic Therapeutics's page on cerebrumdao.com. This looks like a content-duplication artifact on CerebrumDAO's site rather than two independent €75,000 events.
The science
Problem
Protein misfolding/aggregation as a root cause of neurodegeneration.
Approach
Targeting translational fidelity mechanisms directly, developed on the Molecule Catalyst platform.
Why CerebrumDAO supported it
Not publicly documented beyond the project page's framing as addressing a root cause rather than symptoms.
Researchers & founders
- Dr. Dimitri Scherbakov (University of Zurich, Project Lead)
- Dr. Rashid Akbergenov (University of Basel)
Organizations
- University of Zurich
- University of Basel